For follow‑up after retinal vein occlusion (RVO) treatment, what interval is recommended to monitor for neovascularization over the next six months?

• A. Every Two Weeks
• B. Every 3-4 Weeks
• C. Every 6 Months
• D. Annually

Answer: (B)

Neovascularization after retinal vein occlusion can develop even after initial treatment, driven by persistent retinal ischemia and VEGF. Because these abnormal vessels can form within weeks, close surveillance in the first six months is essential to detect iris or angle neovascularization early and treat promptly before complications like neovascular glaucoma or recurrent edema occur. Monitoring about every 3-4 weeks aligns with the typical treatment cadence and allows timely assessment for new vessels and the need for additional therapy. Longer intervals (six months or annually) risk missing early neovascular changes, while overly frequent visits (every two weeks) are usually not necessary unless progression is evident. Regular dilated exams focusing on the iris and angle (with imaging as needed) complete the monitoring strategy.