GPC management includes a short course of which corticosteroid?

• A. Loteprednol 0.5% qid for 1-2 weeks
• B. Prednisolone acetate 1% daily
• C. Dexamethasone 0.1% weekly
• D. Fluorometholone 0.1% monthly

Answer: (A)

Key idea: for managing giant papillary conjunctivitis, a brief course of a corticosteroid with a favorable safety profile is chosen to quickly quell inflammation while minimizing side effects.

Loteprednol 0.5% given four times daily for one to two weeks is ideal because it’s a soft steroid designed to reduce inflammatory symptoms effectively yet carries a lower risk of raising intraocular pressure and other steroid-related side effects when used briefly. This makes it suitable for a short treatment window in GPC.

The other options involve steroids either with higher potency or regimens that aren’t appropriate for a short, controlled course, increasing the chance of unwanted side effects or inadequate control of inflammation.