What is the purpose of AntiVEGF therapy in RVO?

• A. To reduce macular edema and improve vision
• B. To increase intraocular pressure
• C. To cause cataract formation
• D. To treat glaucoma

Answer: (A)

Anti-VEGF therapy in retinal vein occlusion works by blocking VEGF, which rises in response to retinal ischemia and increases the leakage of fluid from retinal vessels. By inhibiting VEGF, this therapy reduces vascular permeability, lessens macular edema, and often improves central vision. This is the intended effect. It is not aimed at increasing intraocular pressure, causing cataracts, or treating glaucoma; those are not goals of the therapy (though injections can cause a temporary rise in IOP as a procedural effect). In practice, treatment involves regular intravitreal injections with monitoring of macular edema via OCT to guide retreatment.